| Element | Recommendation |
|---|---|
| Stim protocol | Long protocol likely — coordinator's expectation given low AMH + age. Clinic runs 3–4 standard protocols; final choice by doctor |
| Medication | Gonal-F + Pergoveris only. No Puregon ("contains urine of menopausal women"). Synthetic = more stable hormone levels |
| Medication cost | ~€1,000–3,000 per cycle depending on dose |
| MOON method | Major Oocytes ONly. After retrieval, embryologist checks each egg's spindle under polarized microscope hourly; each egg is fertilized individually at its own ideal time. Pitched as valuable for low-AMH/older profiles. €375 add-on, not in any package |
| Sperm selection | Sperm Packet for fertilization (included in "IVF All Inclusive"): MAX + Zymot chip (andrology lab) → PIXI or ICSI (embryology lab). Lab picks method per sample |
| Sperm diagnostics | Diagnostic Sperm Packet (separate add-on): DNA fragmentation, maturity, oxidative stress. Distinct from the fertilization packet despite similar name |
| DuoStim | Likely recommended — coordinator expects doctor will propose it. Second stim 3–5 days after first retrieval; body often responds better pre-primed. Note (May 7): Dr. Filková later overrode this — "no DuoStim, we don't have so good experience with that" |
| Transfers | Always single embryo — fresh or frozen, 100% of cases. "Risk of multiples outweighs marginal implantation gain" |
| Lab tech | Time-lapse incubators standard. PGT turnaround 2–3 weeks |
| Item | Detail |
|---|---|
| PGT-A scope | Up to 8 embryos prepaid in "IVF All Inclusive + PGT-A" package. Embryos from multiple cycles pooled and tested together |
| Karyotype | Mandatory. Results from Canada/Hungary accepted; otherwise tested here (in package price) |
| PANDA panel | Recommended (not mandatory) — monogenic carrier screen for both partners (CF, SMA, deafness gene, PKU, etc.) |
| Sex selection | Cannot be guaranteed; preference can be noted for the embryologist. Czech law applies |
| Tier | No PGT-A | + PGT-A (8) | Cumulative |
|---|---|---|---|
| IVF ICSI (basic) Standard ICSI fertilization |
€3,125 | €5,417 | €2,459/cyc |
| IVF SpermPacket Replaces basic ICSI with advanced sperm selection: MACS + ZymotChip + PICSI. Lab decides method per sample. |
€3,500 | €5,792 | €2,875/cyc |
| IVF All Inclusive SpermPacket + karyotype, PANDA Carrier, Diagnostic SpermPacket, EndomeTRIO, Glue, airport transport. PGT-A version is Magenta AI PGT. |
€7,084 | €9,792 | €3,709/cyc |
| Item | A la carte value |
|---|---|
| Karyotype (both partners) — mandatory per Adéla | €522 |
| PANDA Carrier (110-gene carrier screen, both partners) | €1,250 |
| EndomeTRIO (ERA + EMMA + ALICE endometrial tests) | €1,542 |
| Diagnostic SpermPacket (DNA frag, oxidative stress, Immasperm) | €209 |
| Glue for all transfers | €250 |
| Sperm cryo 1 yr | €125 |
| Magenta AI PGT upgrade (replaces standard PGT-A in 9,792 tier) | €625 |
| Airport transport (Prague, Wien, Bratislava) | — |
| Sum of a la carte value | ~€4,500+ |
All-Inclusive premium over SpermPacket is €2,292 (7,084 vs 5,792 with PGT-A: €4,000). If you don't need the add-ons above, the premium doesn't pay off.
| Scenario | Cycle 1 | Cycles 2–3 ea. | 3-cycle total | Per cycle |
|---|---|---|---|---|
| ICSI+PGT-A Cheapest that meets PGT-A goal |
5,417 + 2,000 = 7,417 | 2,459 + 2,000 = 4,459 | €16,335 | €5,445 |
| SpermPacket+PGT-A ← ranking baseline Adéla's default recommendation |
5,792 + 2,000 = 7,792 | 2,875 + 2,000 = 4,875 | €17,542 | €5,847 |
| All-Inclusive+PGT-A Max package — includes karyotype, PANDA, EndomeTRIO |
9,792 + 2,000 = 11,792 | 3,709 + 2,000 = 5,709 | €23,210 | €7,737 |
| Scenario | +MOON (3×) | +Karyotype (1×) | Adjusted total | Per cycle |
|---|---|---|---|---|
| ICSI+PGT-A + MOON + karyotype | +1,125 | +522 | €17,982 | €5,994 |
| SpermPacket+PGT-A + MOON + karyotype | +1,125 | +522 | €19,189 | €6,396 |
| All-Inclusive+PGT-A + MOON (karyotype incl.) | +1,125 | incl. | €24,335 | €8,112 |
| Medications | €1,000–3,000/cycle (not included) |
| FET (after first) | €480 per transfer. One transfer included with each package |
| Storage | First year included. €125/year after. No time cap — indefinite |
| Multi-cycle discount | Not listed publicly — Adéla to check with financial director |
| Interrupted cycles | Post-OPU no fertilization: €1,459 (ICSI/SpermPacket) / €4,375 (All-Inc). Post-OPU with fertilization no PGT: €2,250–5,375 depending on package. |
| Payment schedule | 70% deposit at treatment start, balance before oocyte fertilization |
| ReproGenesis | IVF Cube | Repromeda | |
|---|---|---|---|
| Doctor met | Dr. Martin Maderka | Dr. Eva Stasna | Coordinator only (Adéla); doctor call held May 7 |
| Location | Brno | Prague | Brno (~5hr drive) |
| Consult fee | 50 EUR | Free | Free (coordinator); 125 EUR (doctor, deducted from treatment) |
| Base cycle | 2,990 EUR | 3,300 EUR | 5,417 (ICSI+PGT-A pkg) / 9,792 (All-Inc+PGT-A) |
| Per-cycle (3-cycle) | 6,705 EUR | 6,150 EUR | 5,445 (ICSI pkg) / 7,737 (All-Inc) |
| Preferred med | Menopur | Pergoveris | Gonal-F + Pergoveris (no Puregon) |
| ICSI | Standard | Always | Included in IVF All Inclusive |
| Sperm selection | Not needed if normal | Microfluidic standard | MAX + Zymot + PIXI (in pkg) |
| Time-lapse | Available | Optional extra | Included (TimeLapse MIRI) |
| DuoStim | Possible, last cycle | Not a fan | Coord said likely; doctor (May 7) said no |
| Unique differentiator | — | SHARE cert, flat PGT-A | MOON method, in-house PGT lab |
| PGT-A pricing | 745 + 405/ea | 3,300 EUR flat/batch | Included (up to 8); prepaid across cycles |
| Storage | 430 + 225/yr | Incl. 1 yr | Incl. 1 yr; 125/yr, no cap |
| FET | 690 | 1,250 | 480 |
| Multi-cycle discount | Ask coordinator | None | Ask financial director |
| Transfer policy | Single | Single | Single (strict, 100%) |